Awareness of Genetic Testing for BRCA-Positive Individuals in Turkey

A survey conducted in Türkiye explored the awareness levels of preimplantation genetic testing for monogenic diseases (PGT-M) among individuals who are BRCA-positive. The study involved both physicians and patients to gain a comprehensive understanding of the current knowledge and practices surrounding PGT-M in this specific demographic. BRCA mutations are known to significantly increase the risk of certain cancers, particularly breast and ovarian cancers, making genetic counseling and testing crucial for affected individuals and their families. PGT-M offers an option for individuals with known genetic mutations, like BRCA, to screen embryos created through in vitro fertilization (IVF) for these specific mutations before implantation. This allows for the selection of embryos that are not affected by the inherited genetic condition, thereby reducing the risk of passing it on to future generations. The survey aimed to identify any gaps in awareness or understanding that might hinder access to or utilization of this advanced reproductive technology. Understanding physician perspectives is vital, as they are key in informing patients about their genetic risks and available testing options. Similarly, assessing patient awareness is crucial to ensure they are empowered to make informed decisions about their reproductive health and cancer risk management. The findings are expected to shed light on the current landscape of PGT-M awareness in Türkiye among BRCA-positive individuals and inform potential strategies for improving education and access.